Table 1.
Presence of UG-repeat sequences in UTRs and coding regions
| Organism | Gene/protein | No. of identical nucleotides |
|---|---|---|
| 3′-UTR | ||
| G. polyedra | LBP | 15 |
| Mus musculus | Novel protein kinase | a: 15; b: 13 |
| Trypanosoma cruzi | Kinetoplast-associated protein | 15 |
| Human | Wilm tumor (WT 33) | 15 |
| Human kidney | Cyclophilin C | 14 |
| Human | Wilm tumor WT1 | 14 |
| Human | Endothelial membrane glycoprotein III a | 14 |
| Human | Pre-B cell enhancing factor | 14 |
| Saccharomyces cerevisiae | Polymerase I | 14 |
| Medicago sativa | Heat shock protein | 14 |
| T. cruzi | Surface antigen | 14 |
| D. melanogaster | Dras 1 (ras oncogenes) | 14 |
| Drosophila ananassae | OM (1D) | 14 |
| Tradescantia paludosa | tpc 70 | 14 |
| Ciona intestinalis | Ctm 1 (tropomyosin) | 14 |
| Oryza sativa | MADS-box protein (MADS 3) | 14 |
| Rattus norvegicus | Myogen | 14 |
| M. musculus | G-alpha-13-protein | 14 |
| Xenopus laevis | Integrin beta-1 subunit | 14 |
| M. musculus | Mouse developmental kinase | 13 |
| Chlamydomonas eugametos | Ca-stimulating protein kinase | 13 |
| Human | Serum response factor | 13 |
| 5′-UTR | ||
| Human | TF II A-alpha | 14 |
| D. melanogaster | Ethanolamine kinase | 14 |
| Coding sequence | ||
| M. musculus | NPY-1 receptor | 15 |
A GenBank search (via National Center for Biotechnology Information blast; cut off = 60; alignment = 500) with the central part of the UG-repeat region (UGUGUGUGUUGUGUG) was conducted. Genes with known function containing the 15-nt long sequence or a slightly modified version of it in their 3′-UTR (upper section), 5′ UTR (medium section), or coding sequence (lower section) are listed. A consensus of all 15 nt is indicated by 15. A change of 1 and 2 nt is indicated by 14 and 13, respectively. a and b describe the presence of two repeat units.