Table 4.

Hazard ratio (HR) for survival

	Univariate analysis			Multivariate analysis
	HR	95% CI	p	HR	95% CI	p
Sex						0.945
Female	1			1
Male	1,28	0.82, 2.0	0.28	1.02	0.59, 1.75
Age						0.001
< 70 years	1			1
≥ 70 years	2.04	1.35, 3.09	0.001	2.23	1.41, 3.54
Preoperative stage						0.003
IA (T1 N0 M0)	1			1
IB (T2 N0 M0)	2.00	1.27, 3.17	0.003	1.63	0.92, 2.89
II-IV	4.59	2.34, 9.02	<0.001	4.16	1.92, 9.05
Operation type
Lobectomy	1			1		0.57
Pneumectomy	2.14	1.34, 3.43	0.002	1.37	0.78, 2.43
Bilobectomy	0.94	0.48, 1.85	0.85	0.84	0.40, 1.76
Wedge	0.70	0.17, 2.88	0.62	0.70	0.16, 3.15
Histology						0.32
Adenocarcinoma	1			1
Squamous cell carcinoma	1.51	0.96, 2.37	0.08	0.86	0.48, 1.54
Large cell carcinoma	2.60	1.36, 4.98	0.004	1.79	0.80, 3.99
Other non-small cell carcinoma	0.63	0.19, 2.04	0.44	0.80	0.24, 2.67
Coronary heart disease						0.73
No previous coronary disease	1			1
Previous coronary disease	1.27	0.81, 1.99	0.31	0.91	0.54, 1.54
Pulmonary function						0.013
FEV1 ≥ 80%	1			1
FEV1<80%	2.30	1.45, 3.65	<0.001	1.93	1.14, 3.28

HR = Hazard Ratio. Statistical analysis: Cox Regression analysis method = enter.

p value: univariate: Wald, multivariate: Likelihood ratio.