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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Eur J Immunol. 2008 Nov;38(11):3200–3207. doi: 10.1002/eji.200838614

Figure 4.

Figure 4

Normal positive selection and thymic emigration in pTG2-PTEN transgenic mice (A) Left two panels: CD69 versus TCR staining profiles of DP thymocytes in transgenic (Tg) and their littermate controls (WT). Right two panels: HSA staining of CD4 SP and CD8 SP thymocytes in transgenic mice and their littermates. (B) Quantitative real-time PCR of RORγt, S1P1, and LKLF using sorted DP thymocytes and CD4 SP thymocytes. (C) The total cell number of CD4+ and CD8+ lymph node T cell population from transgenic and WT littermate controls (n=8). The ratio of transgenic/non-transgenic cell number for each cell population is indicated below the graph (p values were measured using Student's t-test). The experiments in panel A were done more than 3 times with similar results, those in panel B were based on triplicate samples and data in panel C were based on 8 pairs of mice.