Table 1.

Body and liver weights and indices of insulin resistance in regular diet (RD) and HFD fed mice.

	WT RD	WT HFD	jnk1-/- HFD	jnk2-/- HFD
Body weight (g)	31.8 ± 1.7	41.7 ± 1.6*	31.2 ± 1.6†	50.6 ± 1.1*†
Liver weight (g)	1.2 ± 0.1	1.6 ± 0.1	1.2 ± 0.1†	1.9 ± 0.1*
Body/liver ratio (%)	3.9 ± 0.2	3.8 ± 0.2	3.8 ± 0.1	3.8 ± 0.1
Glucose (mg/dl)	120 ± 6.7	178 ± 10#	131 ± 6†	157 ± 10#
Insulin (ng/ml)	2.4 ± 0.4	3.6 ± 0.6	1.2 ± 0.2#†	4.1 ± 0.7#
HOMA	16.7 ± 2.4	46.0 ± 9.1*	4.6 ± 0.7#†	80.9 ± 17.5#

^*P<0.05 as compared to wild-type on RD

^#P<0.01 as compared to wild-type on RD

^†P<0.02 as compared to wild-type on HFD. Results are expressed as mean ± SE and each data point represents 6-18 animals.