Table 2.

Electrocardiographic Findings Before, During, and After Ranolazine Infusion

Parameters	Ranolazine Infusion
	Before*	During†	After¶
PR, ms	206±13	200±21	212±19
QRS, ms	88±8	86±11	94±17
RR, ms	1152±253	1108±259	1168±361
QT, ms	576±94	544±100**	590±109
QTc, Fridericia, ms	548±52	526±53††	562±52
QTpeak, ms	484±70	440±64**	492±93
Tpeak-Tend, ms	92±27	106±38	126±60
T duration, ms	184±46	190±37	230±77
T amp, mv	0.26±0.06	0.24±0.06	0.26±0.11

^*Time-matched on Day -1 to 8^th hour of Day 1 ranolazine infusion.

^†At 8^th hour of ranolazine infusion on Day 1.

^¶At 16 hours after ranolazine infusion on Day 1.

^**p<0.01 and

^††p<0.05change from before ranolazine infusion by paired t-test comparison.