Table 3.

Resting Echocardiographic Findings Before and During Ranolazine Infusion

Parameter	Baseline	Ranolazine*
LV volumes
End diastole, ml	126±32	129±42
End systole, ml	47±12	52±17
LV systolic function
LVEF, %	62 ± 8	60 ± 5
Stroke volume, ml	79 ± 25	78 ± 27
Dyssynchrony score, ms	100±57	92±50
LV diastolic function
Isovolumic relaxation time, ms	125 ± 27	109 ± 35†
Mitral E-wave velocity, cm/s	57 ± 8	71 ± 9†
Mitral A-wave velocity, cm/s	50 ± 10	63 ± 12
Mitral E/A ratio	1.2 ± 0.3	1.2 ± 0.3
Mitral E-wave deceleration time, ms	289 ± 80	226 ± 34
Mitral peak annular E velocity, cm/s	7.9 ± 3.6	8.7 ± 3.4

^*At 8^th hour of ranolazine infusion.

^†p<0.05 change from baseline by paired t-test comparison.