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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Nat Cell Biol. 2008 Dec 7;11(1):27–35. doi: 10.1038/ncb1809

Figure 2. Kif2b is required for correction of attachment errors.

Figure 2

a, Spindles of untreated (Control), MCAK-deficient (MCAK RNAi), and Kif2b-deficient (Kif2b RNAi) U2OS cells in the presence of monastrol (top panels) or after recovery from monastrol treatment (bottom panels). b, Number of cells with bipolar spindles that failed to align chromosomes with no treatment (blue) or following recovery from monastrol treatment (red). c, Spindles of untreated (Control), MCAK-deficient (MCAK RNAi), and Kif2b-deficient (Kif2b RNAi) cells following recovery from monastrol treatment in the presence of hesperadin (top panels) and then followed by recovery from hesperadin treatment (bottom panels). d, Number of bipolar cells that failed to align chromosomes after monastrol washout in the presence of hesperadin (blue) and then after recovery from hesperadin treatment (red). Bars in b and d represent mean ± s.e.m, n = 600, 3 experiments cells for b, 100 cells, 2 experiments for d. Scale bars, 5 μm. *, p < 0.0002, t-test.