Table 3.

Number of EGFR, HER2, pPI3K, and pAkt-positive CTCs in breast cancer patients

Number of CTCs per sample	EGFR			HER2		pPI3K		PAkt
	Early disease (n = 16)	Metastatic disease (n = 16)	Early disease (n = 16)	Metastatic disease (n = 16)	Early disease (n = 16)	Metastatic disease (n = 16)	Early disease (n = 16)	Metastatic disease (n = 16)
1	2 (13)	1 (6)	5 (31)	6 (38)	6 (31)	3 (19)	5 (31)	4 (25)
2	4 (25)	1 (6)	1 (6)	2 (13)	5 (31)	2 (13)	4 (25)	3 (19)
3	-	-	-	-	-	4 (25)	1 (6)	2 (13)
4	-	2 (13)	1 (6)	1 (6)	2 (13)		2 (13)	-
≥ 5	-	3 (19)	1 (6)	1 (6)	1 (6)	5 (31)	1 (6)	4 (25)

Values are expressed as number (%). CTC, circulating tumor cell; EGFR, epidermal growth factor receptor; HER, human epidermal growth factor receptor; PI3K, phosphoinositide-3 kinase.