Table 4.

EGFR and HER2 expression in primary tumor and in CTCs

	Early disease				Metastatic disease
	Primary tumor		CTCs		Primary tumor		CTCs
Patient number	HER2	EGFR	HER2	EGFR	HER2	EGFR	HER2	EGFR
1	-	+	+	+	-	-	+	-
2	+a	NA	+	-	+	-	+	-
3	-	-	-	+	+	NA	+	+
4	-	-	+	-	-	-	-	-
5	-	-	+	-	-	-	+	-
6	-	NA	+	+	-	NA	-	-
7	-	+	-	+	+	-	+	-
8	-	-	-	-	-	-	+	-
9	+	-	-	-	-	NA	-	-
10	+	-	+	+	+	-	+	+
11	-	+	-	-	+	NA	-	+
12	-	-	+	-	-	+	-	-
13	-	-	+	-	-	NA	-	+
14	-	-	-	-	-	-	+	+
15	-	NA	-	-	-	NA	+	+
16	NA	NA	-	+	-	-	+	+

^aScore +3 or fluorescence in situ hybridization positive. CTC, circulating tumor cell; EGFR, epidermal growth factor receptor; HER, human epidermal growth factor receptor.