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. 2008 Sep 29;10(5):R81. doi: 10.1186/bcr2150

Table 3.

Distribution of 11q protein staining category in relation to CGH gene profile

Protein expression Gene expression
Deletion Normal Gain/Amp Total P valuea
Cortactin 0.664
 Low/intermediate expression 1 13 5 19
 Over-expression 0 6 3 9
 Total 1 19 8 28

FADD 0.477
 Low/intermediate expression 0 16 7 23
 Over-expression 0 3 3 6
 Total 0 19 10 29

Cyclin D1 0.083
 Low/intermediate expression 3 30 10 43
 Over-expression 0 1 3 4
 Total 3 31 13 47

Pak1 0.027
 Negative 3 28 4 35
 Positive 0 4 5 9
 Total 3 32 9 44

Chk1 0.241b
 0% to 5% (low) 2 6 0 8
 6% to 50% (intermediate) 5 18 0 23
 51% to 100% (high) 0 7 0 7
 Total 7 31 0 38

aCorrelations were calculated using Mann-Whitney test (two-sided) unless otherwise specified. bSpearman's ρ. Amp, amplification; CGH, comparative genomic hybridization; Chk1, checkpoint kinase 1; FADD, Fas-associated death domain; Pak1, p21-activated kinase 1.