Table 1.
Initial cohort of patients (Ninewells Hospital, Dundee, UK): characteristics of the 35 patients with initially ER-positive primary breast cancer
| Characteristic | Control group (n = 17) | TF group (n = 18) | Pa |
| Age (years) | |||
| <70 | 5 | 4 | NS (0.92) |
| ≥ 70 | 12 | 14 | |
| Histological gradeb | |||
| I + II | 14 | 8 | NS (0.11) |
| III | 3 | 8 | |
| Lymph node status | |||
| Node negative | 10 | 4 | NS (0.06) |
| Node positive | 7 | 14 | |
| Macroscopic tumor sizec | |||
| <30 mm | 11 | 6 | NS (0.17) |
| ≥ 30 mm | 6 | 11 |
aP-value (χ2 test) was considered significant when P < 0.05. bInformation available for 33 patients. cInformation available for 34 patients. ER, estrogen receptor; NS, not significant; TF, tamoxifen failure.