Table 7.

Univariate and multivariate analysis of the six genes in relation to OS among the 33 breast cancer samples from the independent cohort (Centre Léon Bérard, Lyon, France)

Genes	Univariate (n = 33)			Multivariate (n = 33)
	HR	95% CI	Pa	HR	95% CI	Pa
ESR1	0.09	0.02 to 0.38	<10-4	0.17	0.03 to 0.86	0.032
FOS	0.12	0.03 to 0.42	<10-4	0.22	0.06 to 1.00	0.049
BCL2	0.07	0.01 to 0.31	<10-4			NS(2)b
SNCG	0.24	0.08 to 0.75	0.008			NS(3)
IGFBP4	0.34	0.12 to 0.98	0.038			NS(1)
MET	1.08	0.40 to 2.88	NS	NDc	ND	ND

^aP value was considered significant when P < 0.05. ^bNS(i), order in which the variable was deleted from the model. ^cND indicates 'not done'; multivariate analysis was done using the variables found to be significant in univariate analysis. CI, confidence interval; HR, hazard ratio; NS, not significant; OS, overall survival.