Table 3.
Hemodynamic, angiographic, echocardiographic, and Doppler measurements obtained before (pretreatment) and after 3 mo of treatment with DARB (posttreatment)
| Pretreatment | Posttreatment | P Value | |
|---|---|---|---|
| HR, beats/min | 78±3 | 81±3 | 0.358 |
| Mean aortic pressure, mmHg | 75±3 | 87±4 | 0.024 |
| LV EDP, mmHg | 16±1 | 11±1 | 0.000 |
| LV EDV, ml | 66±4 | 66±4 | 0.736 |
| LV ESV, ml | 50±3 | 46±4 | 0.004 |
| LV EF, % | 25±0.3 | 30±1 | 0.002 |
| SV, ml | 16±1 | 20±1 | 0.000 |
| CO, l/min | 1.29±0.13 | 1.59±0.09 | 0.003 |
| CI, l·min−1·m−2 | 1.61±0.15 | 1.93±0.12 | 0.008 |
| MR, % | 17.6±1.7 | 15.5±1.9 | 0.087 |
| PE/PA | 1.93±0.10 | 2.26±0.15 | 0.076 |
| DT, ms | 77.0±5.3 | 82.4±6.0 | 0.443 |
| LV EDWS, g/cm2 | 86±6 | 72±5 | 0.043 |
| Hct, % | 44±2 | 59±5 | 0.032 |
| Hgb, g/dl | 15.1±0.6 | 19.3±2.0 | 0.096 |
| ESR, mm/h | 0.43±0.20 | 0.29±0.18 | 0.68 |
Values are means ± SE.