Fig. 6.

Original responses of BP, RSNA, and integrated RSNA during repeated regional myocardial ischemia, before and after treatment with BM 13,177 in a cat following sinoaortic denervation and cervical vagotomy. A: excitatory BP (MAP: 43-mmHg increase) and RSNA (peak integrated RSNA: 37% increase) responses during an initial period of ischemia. B: shows that blockade of thromboxane A₂/prostaglandin endoperoxide (TP) receptors with BM 13,177 (30 mg/kg iv) attenuated the increases in MAP and integrated RSNA during ischemia. Neurograms 1–4 are representative of original RSNA recordings at times indicated by the short line above the integrated RSNA recordings.