Table 1.

Excitatory reflex responses to intrapericardial U-46619

	n	ΔMAP, mmHg		ΔRSNA, %
		Initial	Repeated	Initial	Repeated
−Procaine	8	21±4†	22±5†	20±9†	21±10†
+Procaine	6	22±6†	2±1*	21±8†	−0.3±2.0*
+BM 13,177	7	22±9†	2.5±3*	22±10†	3.1±3.9*
+Tropisetron & pyrilamine	4	25±8†	27±9†	28±11†	26±9.8†

Values are means ± SE; n, no. of cats. Δ, Change; MAP, mean arterial pressure; RSNA, integrated renal sympathetic nerve activity. 2% Procaine was applied in the pericardial space 3 min before repeated application of U-46619 (10 μg). BM 13,117 was injected intravenously 15 min before repeated U-46619 application.

^*P < 0.05 compared with initial response.

^†P < 0.05 compared with respective control.