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Nerve-stimulated overflow of NE (A) and NPY (B) from mesenteric beds of SHRs in the absence (control) or presence of EMD-66684 [0.1 μM; AT1 receptor antagonist (AT1RA)]. Data are plotted as fold increases in NE or NPY overflow. Each bar is the mean ± SE of 5 preparations obtained from 10- to-12-wk-old SHRs. *P < 0.05 compared with control.
