Table 2.

Effect of periarterial NS on neuropeptide Y overflow (ng/ml) from mesenteric arterial beds obtained from WKY rats or SHRs of 4–6, 10–12, or 18–20 wk of age

	WKY			SHR
	Basal	NS	Increase	Basal	NS	Increase
4–6 wk old	0.02±0.03	1.09±0.15	1.07	0.03±0.01	1.14±0.15	1.11
10–12 wk old	0.03±0.004	0.85±0.09	0.82	0.06±0.02	1.19±0.09*	1.13
18–20 wk old	0.07±0.02	1.22±0.18	1.15	0.08±0.02	1.76±0.09*†	1.68

Results are expressed as means ± SE of neuropeptide Y overflow (in ng/ml); n = 5–7 preparations.

^*P < 0.05 compared with WKY rats;

^†P < 0.05 compared with SHRs of 4–6 and 10–12 wk of age.