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Effects of the MEK1/2 inhibitor PD98059 (1 μM), as well as that of IGF-I (10−8 M) in the presence of PD98059, on the current-voltage relationship of IK1 in normal (A) and hypertrophied (B) adult cardiomyocytes. Data are average current density ± SE with n = 5. Inset in each graph shows respective representative IK1 responses at −120 mV.
