Fig. 7.

Tryptase release in vehicle- and ATL146e-treated A_2AAR^+/+ and A_2AAR^−/− BMC mice. A: the percent change in tryptase release was not significantly different in vehicle- and ATL146e-treated hearts from mice where A_2AAR^−/− bone marrow had been transplanted (KO/WT vehicle and ATL146e). B: ATL146e treatment reduced the percent change in tryptase release at every collection period during reperfusion versus vehicle in mice where A_2AAR^+/+ bone marrow was transplanted (WT/WT vehicle and ATL146e). *P < 0.05 by two-way ANOVA with the Student-Neuman-Keuls post test.