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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Mech Dev. 2008 Jun 19;125(9-10):857–864. doi: 10.1016/j.mod.2008.06.006

Fig 1. A diagram of the cyclin E genomic region and of the different cyclin E PNS enhancer constructs.

Fig 1

cyclin E genomic fragments were used to generate a series of nuclear GFP (nGFP) reporter constructs. The numbers on top represent the locations of the cyclin E genomic sequence relative to the translation start of the type I cyclin E transcript. The location of the Kpn I and Nco I restriction sites, which defines the PNS enhancer in the work of Jones et al. (2000) are indicated. Asterisks indicate the locations of the two TCF-binding sites in the cyclin E PNS enhancer. The presence or absence of GFP expression is indicated by plus or minus signs, respectively. The number of plus signs indicates the level of GFP expression relative to the full-length 4.6-PNS enhancer.