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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Placenta. 2008 Aug 8;29(9):763–771. doi: 10.1016/j.placenta.2008.06.011

Figure 1. Classic Renin-Angiotensin System Cascade.

Figure 1

ANG II, the key effector molecule of the RAS and potent vasoconstrictor, acts through AT1 receptors to increase blood pressure. AT1 receptors are found on many cell types. Abbreviations - ADH: Antidiuretic hormone, ANG II: Angiotensin II, AT1 receptor: angiotensin-II type I receptor.