Table 1.

Brain Regions Correlated with Freezing Duration

NEC	Brain Region	mm3	Max t	x	y	z
Positive Correlation	BNST/NAC	26.37	6.08	3.125	1.875	−1.25
Negative Correlation	Area 4 (motor ctx), Area 2 (somatosensory ctx), and Parietal areas (PE, POa, PG)	1592.04	6.41	14.375	−18.125	18.125
	White matter bordering ventral Area 46	48.83	4.65	−15	11.875	7.5
AL	Brain Region	mm3	Max t	x	y	z
Positive Correlation	BNST/NAC	36.38	4.09	−4.375	2.5	.625
	Lateral Geniculate, External Medullary Lamina, Reticular Thalamic Nucleus	26.37	4.32	15	−14.375	−1.25
	White Matter bordering PG associated area of the superior temporal sulcus	9.52	3.38	−17.5	−3.125	−6.875
Negative Correlation	Areas 1, 2, 3 (somatosensory ctx), Area 4 (motor ctx)	156.25	5.00	−11.25	−10	22.5
	Area 2 (somatosensory ctx)	45.41	4.33	−1.875	−16.25	17.5
	Area 4 (motor ctx)	27.34	3.91	−16.25	−5	16.25
	Parietal Area PEa	15.63	4.11	−15	−15	16.875
	Area 4 (motor ctx)	13.92	3.48	17.5	−5	15.625
	Parietal Area PEa	11.96	3.70	15	−14.375	15.625

Significant (p <.005 uncorrected) clusters resulting from a voxelwise correlation between brain activity and log duration of freezing behavior controlling for age in the NEC and ALN conditions. All clusters larger than 8 mm³ are included. (Posterior regions of the brain were excluded as described in the Methods and Materials.) Anatomical definitions of the clusters were made based on the rhesus monkey atlas (Paxinos et al 2000). Data presented include the size of the cluster (mm³), the maximum t-value within the cluster, and the corresponding x (left to right), y (posterior to anterior) and z (inferior to superior) coordinates in mm relative to the center of the anterior commissure. The clusters are presented in descending order based on their size. ALN, alone group; NEC, no eye contact group; BNST, bed nucleus of the stria terminalis; NAC, nucleus accumbens; MRI, magnetic resonance imaging; ROI, regions of interest.