Table 3.
Inheritance of AR alleles in sons of mothers with skewed X inactivation
| Child Diagnosis | Mom Age (Y) | Mom XCI % Skewing |
Mom small allele (bp) |
Mom large allele (bp) |
allele son inherited (bp) |
did son inherit skewed allele? |
|---|---|---|---|---|---|---|
| ASD | 36.3 | 92.0 | 279 | 282 | 282 | no |
| ASD | 36.3 | 85.0 | 286 | 292 | 286 | yes |
| ASD | 32.4 | 97.1 | 270 | 276 | ND | ND |
| Autism | 43.2 | 3.0 | 276 | 299 | 276 | no |
| Autism | 31.4 | 12.9 | 284 | 297 | 297 | yes |
| Autism | 37.5 | 12.1 | 277 | 291 | 291 | yes |
| Autism | 30.8 | 91.1 | 273 | 293 | 273 | yes |
| Delayed | 28.0 | 85.7 | 276 | 279 | ND | ND |
| Delayed | 39.5 | 12.7 | 271 | 282 | ND | ND |
| Delayed | 36.2 | 6.9 | 274 | 277 | 277 | yes |
| Typical | 35.1 | 93.4 | 267 | 276 | 276 | no |
| Typical | 25.6 | 96.6 | 270 | 276 | 270 | yes |
| Typical | 34.1 | 14.4 | 270 | 279 | 270 | no |
| Typical | 32.6 | 14.8 | 282 | 285 | 285 | yes |