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Epidermal expression of TNF-alpha-mRNA on POD 3, 7 and 10 in semi-occluded and non-occluded wounds. TNF-alpha expression was significantly downregulated in semi-occluded wounds on POD 3 but not at later timepoints. Comparable to IL-1-alpha, mRNA-TNF-alpha expression patterns were almost even in semi-occluded and non-occluded wounds on POD 10 paralleling the histological findings.
