Table III.
Comparison of M2 genes expressed in HCMV-infected monocytes/macrophagesa
| Category and Full Gene Name | Gene Title | Probe Set | Fold Change |
|---|---|---|---|
| Membrane Receptors | |||
| Chemokine (C-X-C motif) receptor 4 | CXCR4 | 649_s_at | -2.5 |
| Transforming growth factor, beta receptor II (70/80kDa) | TGFBR2 | 1814_at | -2.7 |
| Histamine receptor H1 | HRH1 | 35384_at | nc |
| Toll-like receptor 5 | TLR5 | 34473_at | nc |
| Type I transmembrane C-type lectin receptor DCL-1 | DCL-1 | 34760_at | nc |
| Macrophage scavenger receptor 1 | MSR1 | 39981_at | nc |
| G protein-coupled receptor 105 | GPR105 | 33462_at | nc |
| CD209 antigen-like | CD209L | 39270_at | nc |
| CD36 antigen (collagen type I receptor, thrombospondin receptor) | CD36 | 36656_at | nc |
| Mannose receptor, C type 1 | MRC1 | 36908_at | nc |
| Cytokine and Chemokines | |||
| Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | CCL18 | 32128_at | 39.4 |
| Chemokine (C-C motif) ligand 23 | CCL23 | 36444_s_at | 3.5 |
| Insulin-like growth factor 1 (somatomedin C) | IGF1 | 1501_at | nc |
| Chemokine (C-C motif) ligand 13 | CCL13 | 37454_at | nc |
| Solute Carriers | |||
| Solute carrier family 4, sodium bicarbonate cotransporter, member 7 | SLC4A7 | 34936_at | -1.5 |
| Solute carrier family 38, member 6 | SLC38A6 | 36758_at | nc |
| Enzymes | |||
| Leukotriene A4 hydrolase | LTA4H | 38081_at | -5.5 |
| Cathepsin C | CTSC | 133_at | nc |
| Hexosaminidase B (beta polypeptide) | HEXB | 34888_at | nc |
| Lipase A, lysosomal acid, cholesterol esterase (Wolman disease) | LIPA | 38745_at | nc |
| Adenosine kinase | ADK | 168_at | nc |
| Histamine N-methyltransferase | HNMT | 37604_at | nc |
| Tyrosylprotein sulfotransferase 2 | TPST2 | 35172_at | nc |
| Heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | HS3ST1 | 41555_at | nc |
| Carbonic anhydrase II | CA2 | 40095_at | nc |
| Arachidonate 15-lipoxygenase | ALOX15 | 34636_at | nc |
| Heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | HS3ST1 | 41555_at | nc |
| Extracellular Matrix | |||
| Transforming growth factor, beta 1 (Camurati-Engelmann disease) | TGFB1 | 1830_s_at | -1.6 |
| Fibrinogen-like 2 | FGL2 | 39593_at | -6.7 |
| Selenoprotein P, plasma, 1 | SEPP1 | 34363_at | nc |
| Chimerin (chimaerin) 2 | CHN2 | 33244_at | nc |
| Fibronectin 1 | FN1 | 31719_at | nc |
| DNA-binding Factors | |||
| Growth arrest-specific 7 | GAS7 | 33387_at | nc |
| Early growth response 2 (Krox-20 homolog, Drosophila) | EGR2 | 37863_at | nc |
| V-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | MAF | 41504_s_at | nc |
a
Examined M2 genes are based on the transcriptional profiling work of Martinez et al. (47).