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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Nat Struct Mol Biol. 2008 Dec 21;16(1):30–34. doi: 10.1038/nsmb.1531

Figure 2.

Figure 2

Analysis of inter and intra-subunit interactions in the closed (a) and open (b) structures of the NaK channel. The numbers in the boxed regions in both structures correspond to the zoom-in panels 1-3 for the closed structure and 1-2 for the open NaK structure. Zoom 1 in both cases highlights intra-subunit interactions between outer (M1) and inner (M2) helices. Zoom 2 highlights inter-subunit interactions between inner helices of two neighboring subunits. Zoom 3 shows an intracellular view of the interactions involved in the bundle crossing formation in the closed structure.