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. Author manuscript; available in PMC: 2009 Sep 22.
Published in final edited form as: Neuroscience. 2008 Jul 12;156(1):30–41. doi: 10.1016/j.neuroscience.2008.07.016

Figure 3.

Figure 3

The development of ALO AIMs and rotations in rats chronically treated with CORT and l-DOPA. From days 1–9, rats received either CORT (1.25 mg/kg or 3.75 mg/kg) and l-DOPA (4 mg/kg + 15 mg/kg of benserazide) or Vehicle (16% EtOH, 44% propylene glycol, 40% phosphate buffer saline) and l-DOPA. From days 10 –15, rats only received l-DOPA (shaded region). The development of ALO AIMs was delayed in rats co-administered CORT and l-DOPA on days 1, 3, and 5. LID developed once CORT treatment ceased (see day 15). All symbols denote p<0.05. (* Vehicle vs. 3.75 mg/kg; + vehicle vs. 1.25 mg/kg). Data are presented as mean ± 1 SEM.