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. Author manuscript; available in PMC: 2009 Sep 22.
Published in final edited form as: Neuroscience. 2008 Jul 12;156(1):30–41. doi: 10.1016/j.neuroscience.2008.07.016

Figure 5.

Figure 5

Role of IL-1β in the expression of l-DOPA-induced ALO AIMs and rotations. L-DOPA-primed rats were intrastriatally microinjected with IL-1ra (10-µg or 100-µg) or Vehicle (sterile saline) followed by an immediate systemic injection of l-DOPA (4 mg/kg + 15 mg/kg of benserazide) and assessed for AIMs and rotations for 2 hrs. Rats receiving 100-µg IL-1ra showed a reduction in AIMs and rotations compared to vehicle treated rats (* 100-µg vs. VEH, p<0.05). Data are presented as mean ± 1 SEM.