Table 2.
Tumors detected in Mdm2-a hemizygous transgenic mice and wild-type littermates
Mouse line | Number of tumors/total (%) | Tumor types (number of animals) | Age at death (months) |
---|---|---|---|
Wild-type | 2/55 (4) | Squamous cell carcinoma (1) | 25 |
Soft tissue sarcoma (1) | 24 | ||
Mdm2-a transgenic | 4/64 (6) | Alveolar bronchiolar adenoma (1) | 12 |
Soft tissue sarcoma (1) | 19 | ||
Osteoma (1) | 8 | ||
Soft tissue mass* leg (1) | 13 |
Diagnosis unclear.