Fig. 6.

Thermodynamic interactions of LPS and PQS. Isothermal titration of (A) pure PE, (B) PE + HHQ and (C) PE + PQS mixtures into P. aeruginosa LPS aggregates. Quinolones were added to PE to increase solubility. Three microlitres of PE alone or PE : quinolone mixtures were titrated into the LPS-containing cell every 5 min. Measurements were performed at 37°C with constant stirring. Values plotted for HHQ and PQS experiments (B and C) represent values after subtraction of PE alone measurements (A). Data represent triplicate measurements.