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. 2009 Jan 19;4(1):e3914. doi: 10.1371/journal.pone.0003914

Figure 9. mRNA expression of MMP-1 and MMP-13.

Figure 9

A–D. MMP-1 In situ hybridization of sections of frontoparietal bone from various stages (antisense probes), 20× magnification. A′–D′. 40× magnification of same area. E. Representative sense probe of stage 60 to demonstrate lack of non-specific staining. Brown staining represents positive localization, blue represent hematoxylin counterstaining. F–I. MMP-13 In situ hybridization of sections of frontoparietal bone from various stages (antisense probes), 20× magnification. F′–I′. 40× magnification of same area. J. Representative sense probe of stage 60. Note increased brown staining in Stage 56 and 60 with both probes.