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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: J Pharmacol Exp Ther. 2008 Aug 6;327(2):402–410. doi: 10.1124/jpet.108.142372

Fig. 1.

Fig. 1

Time lines and protocols for all experimental groups. After 30 min of stabilization, all mice underwent 30-min LAD occlusion followed by 60-min reperfusion represented with a sequence of white/black/white horizontal boxes. Group 1 (n = 7), WT mice subjected to 30-min LAD occlusion and 60-min reperfusion with intravenous injection of PBS 5 min before reperfusion. Groups 2 (n = 7), 5 (n = 7), and 6 (n = 7), WT mouse hearts subjected to 30-min ischemia and 60-min reperfusion with intravenous bolus infusion of SODm, EUK134, and SODm plus glibenclamide 5 min before reperfusion. Groups 3 (n = 7) and 4 (n = 7), eNOS−/− mouse hearts subjected to 30-min ischemia and 60-min reperfusion with intravenous bolus infusion of SODm 30 min before ischemia. Additional groups of hearts were subjected to 30-min ischemia and 24-h reperfusion for measurements of infarct size and area at risk.