Table 1.
Clinical characteristics of patients with monomicrobial and polymicrobial P. aeruginosa bacteremia+
| Characteristic | Monomicrobial N=51 | Polymicrobial N=18 |
|---|---|---|
| Age | 69.0 (49.0-81.0) | 78.0 (64.8-82.3) |
| Male gender | 35 (68.6) | 10 (55.6) |
| Non-white race | 2 (3.9) | 2 (11.1) |
| Diabetes mellitus | 12 (23.5) | 1 (5.6) |
| End stage renal disease | 5 (9.8) | 0 (0) |
| Malignancy | 23 (45.1) | 6 (33.3) |
| Hematologic | 10 (19.6) | 3 (16.7) |
| Solid tumor | 13 (25.5) | 3 (16.7) |
| Immunocompromised | 20 (39.2) | 5 (27.8) |
| Chemotherapy | 11 (21.6) | 4 (22.2) |
| Corticosteroids | 9 (17.6) | 1 (5.6) |
| Neutropenia | 8 (15.7) | 3 (16.7) |
| Other immunosuppressive medications | 4 (7.8) | 1 (5.6) |
| Transplant recipients | 3 (5.9) | 0 (0) |
| Recent surgical procedure | 18 (35.3) | 1 (5.6) |
| Central venous catheter | 21 (41.2) | 1 (5.6) |
| Foley catheter | 11 (21.6) | 1 (5.6) |
| Prior antibiotic therapy | 21 (41.2) | 3 (16.7) |
| Classification: | ||
| Nosocomial | 11 (21.6) | 1 (5.6) |
| Health care-associated | 29 (56.9) | 8 (44.4) |
| Community-acquired* | 11 (21.6) | 9 (50.0) |
| ICU admission | 12 (23.5) | 7 (38.9) |
| Hypotension | 19 (37.3) | 4 (22.2) |
| Fever/hypothermia | 32 (62.7) | 13 (72.2) |
| Leukocytosis | 27 (52.9) | 9 (52.9) |
| Leukopenia | 12 (23.5) | 5 (29.4) |
| Pitt bacteremia score ≥ 4 | 11 (21.6) | 4 (22.2) |
| Source: | ||
| Urinary tract | 16 (31.4) | 4 (22.2) |
| Abdominal/biliary** | 1 (2.0) | 5 (27.8) |
| Respiratory tract | 11 (21.6) | 4 (22.2) |
| Catheter-related | 5 (9.8) | 0 (0) |
| Skin and soft tissue | 3 (5.9) | 0 (0) |
| Primary bacteremia++ | 15 (29.4) | 5 (27.8) |
| 28-day all-cause mortality | 13 (25.5) | 4 (22.2) |
+
Continuous data are expressed as median (interquartile range), whereas categorical data are the observed number (%) for each level.
++
Primary bacteremia is defined as bacteremia with no clearly established site of active infection.
*
p=0.022,
**
p=0.0038 (only p values <0.05 are shown).