Figure 9.
Stereo comparison of the ternary complex of mDHFR with NADPH and PT684a (green), pcDHFR with PT653 (cyan; Cody et al., 2002 ▶) and a model of PT682 (yellow). Note that the carboxylate group clashes with Arg70.
Stereo comparison of the ternary complex of mDHFR with NADPH and PT684a (green), pcDHFR with PT653 (cyan; Cody et al., 2002 ▶) and a model of PT682 (yellow). Note that the carboxylate group clashes with Arg70.