. Author manuscript; available in PMC: 2010 Jan 1.

Published in final edited form as: J Liq Chromatogr Relat Technol. 2009 Jan;32(2):261–272. doi: 10.1080/10826070802603351

Table 1.

Accuracy and Repeatability for Assaying NSC 737664 in Human Plasma by HPLC with UV Detection and Verification of Peak Identity by MS

	UV Detection			MS Detection
Concentration Added (μM)	Accuracy (%)	Repeatability (%)	S/N	Accuracy (%)	Repeatability (%)	S/N
5.0	104.2	11.6		96.8	10.2
2.5	98.0	9.2		96.0	10.6
1.0	95.0	10.8		105.0	10.0
0.50	110.0	12.3		130.0	21.9
0.25	104.0	11.8		136.0	31.8
0.10	94.0	18.4	10	97.0	29.7	18

Accuracy and repeatability of the assay were assessed from 12 different standard curves of NSC 737664 in human plasma separately prepared and analyzed over a 44-week period.