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. Author manuscript; available in PMC: 2009 Sep 23.
Published in final edited form as: Curr Biol. 2008 Sep 23;18(18):1355–1364. doi: 10.1016/j.cub.2008.07.097

Figure 4. Inhibition of CeTOR or Box C/D snoRNPs decreases the rate of newly synthesized proteins.

Figure 4

Relative levels of 35S-methionine incorporation in 2-day-old fog-1(q253ts) adult animals treated with either empty vector (EV), let-363(RNAi); daf-15(RNAi) (TOR), ruvb-1(RNAi), fib-1(RNAi), pha-4(RNAi) or ife-2(RNAi). RNAi was initiated at the L4 stage (“day 0” of adulthood) at 25°C. Bar graphs represent average 35S-methionine incorporation normalized to total protein levels for different RNAi treatments compared to EV(RNAi) (**p<0.006, *p<0.0002, one-sided paired t-test. error bars represent SEM, N, number of measurements).