Table 1.
Parameter | Groups with progressively decreasing glucose |
p | |
---|---|---|---|
Fasted rats (n = 25) | Nonfasted rats (n = 22) | ||
Incidence of any seizure symptom | 25 of 25 (100%) | 10 of 22 (45.5%) | <0.0001 |
Peripheral glucose at the first seizure onset | 20.0 ± 0.5 mg/100 ml (n = 25) | 18.3 ± 1.4 mg/100 ml (n = 10) | NS |
Latency to the onset of the first seizure | 100.1 ± 3.8 min (n = 25) | 172.4 ± 10.3 min (n = 10) | < 0.0001 |
Latency to the onset of the first seizure from the beginning of significant hypoglycemia (defined as 40 mg/100 ml) | 78.0 ± 3.8 min (n = 25) | 106.0 ± 10.3 min (n = 10) | <0.01 |