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. 2009 Jan 16;284(3):1755–1764. doi: 10.1074/jbc.M807210200

FIGURE 3.

FIGURE 3.

Surface pressure-molecular area isotherms for mixed monolayers of oxysterols and DOPC or DPPC. DOPC and DPPC monolayer mixtures were prepared containing 25-HC (A), 27-HC (B), 7α-HC (C), 7β-HC (D), 7-KC (E), and cholesterol (F). Molecular areas are plotted versus the mole fraction of sterol at a constant surface pressure of 5 millinewtons/m (solid lines). Dashed lines represent the theoretical ideal (non-interacting) mixture of the pure components. Increased mean molecular area versus ideal isotherm indicates membrane expansion effects of sterols, whereas decreased mean molecular area versus ideal isotherm indicates membrane-condensing effects of sterols.