TABLE 1.

Parameters of IV and (ΔF/F)_max data

Values represent mean (±S.E.) for n number of mice (from a total of 32 PLC^+/+ and 27 PLC^-/- myocytes). Parameters for the voltage dependence of Ca²⁺ current (I-V) was obtained by fitting myocytes within each group separately to the appropriate equation (I-V, Equation 1) as described under “Experimental Procedures,” (ΔF/F)_max values are the mean (±S.E.) values obtained at a test potential of -10 mV.

	Gmaxa	kv	VG1/2	Vrev	(ΔF/F)max
	nS/nF		mV
PLCε+/+ naïve (n = 5 mice)	108 ± 14	7.4 ± 0.4	-14.3 ± 0.4	62.9 ± 1.1	0.15 ± 0.04
PLCε+/+ Iso (n = 5 mice)	197 ± 14b	6.1 ± 1.4	-18.9 ± 1.7	65.0 ± 0.9	0.45 ± 0.04b,c
PLCε-/- naïve (n = 5 mice)	103 ± 14	6.6 ± 0.3	-16.0 ± 2.4	64.7 ± 1.6	0.15 ± 0.03
PLCε-/- Iso (n = 5 mice)	162 ± 18d	6.0 ± 0.2	-20.1 ± 2.0	66.2 ± 1.9	0.27 ± 0.04d

^aG_max, maximal l-channel conductance; V_rev, reversal potential; V_G1/2, potential at which G is half-maximal, respectively; k_G, slope factor for I-V.

^bp < 0.01 compared to PLCε^+/+ naive.

^cp < 0.05 compared to PLCε^-/- Iso.

^dp < 0.05 compared to PLCε^-/- naive.