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Otoferlin C2 interaction kinetic constants
Each association and dissociation value was determined from five different concentrations.
| Binding partners | ka | kd | KD |
|---|---|---|---|
| m-1 s-1 | s-1 | m | |
| Syntaxin 1A + C2F | 2.6 × 105 | 6.7 × 10-4 | 2.6 × 10-9 |
| Syntaxin 1A + C2D | 1.1 × 103 | 1.9 × 10-2 | 1.7 × 10-5 |
| SNAP-25 + C2F | 5.4 × 103 | 9.0 × 10-4 | 1.7 × 10-7 |
| Cav1.3 + C2D | 3.7 × 104 | 5.3 × 10-3 | 1.4 × 10-7 |
