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. Author manuscript; available in PMC: 2009 Jan 9.
Published in final edited form as: Nature. 2006 Sep 27;443(7111):578–581. doi: 10.1038/nature05181

Figure 2. Increased and earlier expression of genes associated with the activation of key immune cells in mouse lung infected with r1918 influenza virus.

Figure 2

Expression of selected immune-cell-related genes in the lungs of mice infected with Tx91, 2:6 1918, 5:3 1918 or r1918 viruses on days 1, 3 and 5 after infection, as determined by expression microarray analysis. For each infection point, the data presented are the error-weighted average expression changes calculated from four technical replicate arrays performed on three individual mice (n = 12 total). Genes shown in red were upregulated and genes shown in green were downregulated in infected relative to mock-infected mouse lung. NK, natural killer; TH1, T helper 1.