Table 2.
Reported AUF1 target mRNAs bearing the AU–rich signature motif
| Position in 3′UTR | # hits | Name | Symbol | UniGene | Reference |
|---|---|---|---|---|---|
| 410–442, 1378–1411, 1581–1615 | 3 | Cyclin D1 | CCND1 | Hs#S3987156 | (25,37) |
| 45–99 | 1 | Cyclin B1 | CCNB1 | Hs#S3618391 | (unpublished) |
| 291–326, 457–488 | 2 | Gadd45A | GADD45A | Hs#S1731372 | (36) |
| 492–529, 592–624 | 2 | p16 | CDKN2A | Hs#S4001849 | (53) |
| 210–248 | 1 | IL8 | IL8 | Hs#S3218902 | (54) |
| 648–680 | 1 | TNFa | TNF | Hs#S3218906 | (55) |
| 1783–1831, 2389–2429 | 2 | Estrogen receptor a | ESR1 | Hs#S1726719 | (56) |
| 423–454 | 1 | TS | TS | Hs#S1728128 | (57) |
| 939–970, 1433–1473, 1807–1840, 1885–1917, 2189–2220 | 5 | Cyclooxygenase–2 | PTGS2 | Hs#S1730801 | (38) |
| 227–265, 3976–4013, 4373–4407, 4957–4989 | 4 | Bcl–2 | BCL2 | Hs#S1730182 | (58) |
List of known AUF1 target mRNAs, out of a total of 15 best–characterized AUF1 target mRNAs previously reported. The positions of the motif hits within the 3′UTRs are indicated. Overlapping motifs are listed as one.