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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Drug Metab Dispos. 2008 Jul 24;36(10):2104–2112. doi: 10.1124/dmd.108.021857

Figure 5.

Figure 5

Relative formation of isoliquiritigenin metabolites by recombinant UGT enzymes (0.5 mg protein/mL). In each sample, recombinant UGT was incubated with 10 µM isoliquiritigenin at 37 °C for 20 min in the presence of UDPGA (5 mM). A) MG3 formation; B) MG4 formation; and C) MG5 formation. The control incubations contained no enzymes.

*Significant difference compared to the control as determined using one-way ANOVA with the Tukey’s test, p ≤ 0.01 (Mean ± Std. Error; N = 3). All data were normalized to the yield of MG5 (100%) catalyzed by UGT1A10.