Table 3.
Estimated risk of postnatal RPD, obstruction, or VUR according to RP size and gestational age at diagnosisa
| Gestation | 20 wk, 6 mm | 20 wk, 7 mm | 20 wk, 12 mm | 25 wk, 8 mm | 28 wk, 7 mm | 34 wk, 14 mm |
|---|---|---|---|---|---|---|
| Size | (95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) |
| Postnatal RPD at 6 wk | 31% | 47% | 97% | 40% | 15% | 88% |
| (14 to 54) | (25 to 71) | (89 to 99) | (22 to 60) | (5 to 35) | (52 to 98) | |
| Postnatal RPD at study end | 18% | 31% | 95% (77 to 99) | 29% | 10% (3,33) | 89% |
| (5 to 44) | (11 to 62) | (12 to 55) | (40 to 99) | |||
| Obstruction | 2% | 4% | 26% | 4% | * | * |
| (1, 9) | (1, 12) | (9, 57) | (1, 20) | |||
| VUR | 4% | 5% | 15% | 6% | 5% | 18% |
| (2 to 10) | (2 to 12) | (4 to 45) | (3 to 11) | (2 to 12) | (4 to 55) |
Fitted estimates of patient-based data from unselected groups were generated from the following equations:
a) Odds of persistent RPD within first 6 wk = 0.37 × (2.03)RP size × (0.82)gestation
b) Odds of persistent RPD at the end of study = 0.07 × (2.12)RP size × (0.84)gestation
c) Odds of obstruction = 0.01 × (1.56)RP size × (0.92)gestation
d) Odds of VUR = 0.01 × (1.25)RP size × (0.99)gestation
Note: These are estimated equations and estimates must be viewed with caution because of potential for uncontrolled confounding within meta-analyses.
There were no studies with values for obstruction after 26 wk so it was not possible to generate statistically robust estimates at the 28- and 34-wk stages.
RPD, renal pelvis dilation; VUR, vesicoureteric reflux; MCUG, micturating cysto-urethrogram; CI, confidence interval.