Table 3.
Renal biopsy findings
| Parameter | Group A (n = 21) | Group B (n = 12) | P |
|---|---|---|---|
| Patients with AMR (n [%])a | 1 (5) | 3 (25) | 0.12c |
| Patients with clinical AMR (n [%])b | 1 (5) | 3 (25) | 0.12c |
| Patients with ACR (including clinical and subclinical; n [%])a | 7 (33) | 4 (33) | 0.99c |
| ACR type (Banff ’97)a | 0.82c | ||
| none or borderline | 14 | 8 | |
| 1A | 0 | 1 | |
| 1B | 2 | 1 | |
| 2A | 5 | 2 | |
| Patients with BKV (n [%])a | 5 (24) | 2 (17) | 0.99c |
| Patients with recurrent FSGS (n [%])a | 1 (5) | 1 (8) | 0.99c |
| (cg + ci + ct + cv) | |||
| at initial protocol biopsy | |||
| mean ± SD | 1.52 ± 1.29 | 1.33 ± 1.37 | 0.72d |
| range | 0 to 4 | 0 to 5 | |
| at 6-mo protocol biopsy | |||
| mean ± SD | 1.86 ± 1.82 | 3.00 ± 2.57 | 0.22d |
| range (n) | 0 to 7 (21) | 0 to 9 (11) | |
| difference | |||
| mean ± SD | 0.33 ± 1.71 | 1.64 ± 2.38 | 0.044d |
| range | −1 to 6 | −2 to 7 | |
| at 12 mo protocol biopsy | |||
| mean ± SD | 2.53 ± 1.22 | 3.89 ± 2.42 | 0.032d |
| range (n) | 1 to 6 (19) | 0 to 9 (9) | |
| difference | |||
| mean ± SD | 1.21 ± 1.27 | 2.44 ± 1.74 | 0.030d |
| range | 0 to 5 | −1 to 5 |
a
On any biopsy of the graft in question during the first year after transplantation. When more than one biopsy showed ACR, the highest Banff ’97 type (grade) of ACR is listed.
b
On any nonprotocol biopsy of the graft in question during the first year after transplantation, done because of a rise in SCr.
c
By Fisher exact test.
d
By Wilcoxon rank sum test.