Table 2.
Filtration dynamics
| Parameter | Youthful (n = 20) | Aging (n = 17) |
|---|---|---|
| Recipient age (yr) | 46 ± 15a | 64 ± 6 |
| Serum creatinine (mg/dl) | 0.9 ± 0.4a | 1.2 ± 0.5 |
| GFR (ml/min per 1.73 m2) | 69 ± 17a | 48 ± 21 |
| RPF (ml/min per 1.73 m2) | 304 ± 71a | 248 ± 76 |
| Filtration fraction | 0.24 ± 0.06a | 0.19 ± 0.06 |
| Mean arterial pressure (mmHg) | 90 ± 10 | 93 ± 10 |
| πA (mmHg) | 25.4 ± 2.3 | 24.2 ± 1.9 |
| πGC (mmHg) | 29.0 ± 3.3a | 26.6 ± 2.5 |
| Whole-kidney Kf (ml/[min · mmHg]) | 6.6 ± 3.4a,b | 3.7 ± 2.2 b or 2.5 ± 1.9c |
a
P < 0.05.
b
Assume ΔP = 40 or
c
ΔP = 45.