Table 1.
Parameter | WT | TSLP-Control | TSLP-Imatinib |
---|---|---|---|
% GTA occupied by silver-stained matrix | 6.25 ± 0.95 | 14.27 ± 0.11b | 6.79 ± 0.66d |
Cell number/glomerular cross-section | 32.70 ± 1.34 | 38.13 ± 0.69c | 38.70 ± 1.91c |
% GTA occupied by collagen type IV–stained matrix | 10.47 ± 0.43 | 17.06 ± 1.48b | 13.46 ± 0.68e |
% GTA occupied by α-SMA–expressing cells | 0.65 ± 0.06 | 1.76 ± 0.17b | 1.26 ± 0.24f |
GTA occupied by Mac-2–expressing cells (μm2) | 4.98 ± 1.18 | 61.36 ± 11.89b | 142.33 ± 51.98c,e |
Data are means ± SEM.
P < 0.001,
P < 0.01 versus WT mice.
P < 0.001,
P < 0.05,
P < 0.01 versus control TSLP-Tg mice.