Table 1. Quantity of eosinophils in the gastrointestinal tract of children.
The table above illustrates eosinophil levels in the gastrointestinal tract of children (n=28) without apparent gastrointestinal disease. Note that eosinophils are present throughout the healthy gastrointestinal tract, except for the esophagus. Irrespective of gut location, eosinophils are most abundant in the lamina propria and are typically present at much lower levels in the surface epithelium and crypt/glandular epithelium. 1
Gastrointestinal Segment | Lamina Propria | Villous Lamina Propria | Surface Epithelium | Crypt/Glandular Epithelium | ||||
---|---|---|---|---|---|---|---|---|
Mean | Max | Mean | Max | Mean | Max | Mean | Max | |
Esophagus | N/A | N/A | N/A | N/A | 0.03 +/0.10 | 1 | N/A | N/A |
Antrum | 1.9 +/- 1.3 | 8 | N/A | N/A | 0.0 +/- 0.0 | 0 | 0.02 +/- 0.04 | 1 |
Fundus | 2.1 +/- 2.4 | 11 | N/A | N/A | 0.0 +/- 0.0 | 0 | 0.008 +/-0.03 | 1 |
Duodenum | 9.6 +/- 5.3 | 26 | 2.1 +/- 1.4 | 9 | 0.06 +/- 0.09 | 2 | 0.26 +/- 0.36 | 6 |
Ileum | 12.4 +/- 5.4 | 28 | 4.8 +/- 2.8 | 15 | 0.47 +/- 0.25 | 4 | 0.80 +/- 0.51 | 4 |
Ascending Colon | 20.3 +/- 8.2 | 50 | N/A | N/A | 0.29 +/- 0.25 | 3 | 1.4 +/- 1.2 | 11 |
Transverse Colon | 16.3 +/- 5.6 | 42 | N/A | N/A | 0.22 +/- 0.39 | 4 | 0.77 +/- 0.61 | 4 |
Rectum | 8.3 +/- 5.9 | 32 | N/A | N/A | 0.15 +/- 0.13 | 2 | 1.2 +/- 1.1 | 9 |
N=28
The mean number of eosinophils/hpf +/- the S.D. for each an atomical region of the gastrointestinal tract and each region of the mucosa is shown. N/A, not applicable.
This table has been adapted with permission from publisher.