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Capacity of human leptin to enhance cytokine production by primary macrophages. In 3-hr cultures of 5 × 106 cells/ml of C57BL/6 or GM-CSF transgenic peritoneal cells, addition of 50 ng of human leptin stimulated the production of GM-CSF and G-CSF. Mean data from three experiments using triplicate cultures ± SD (note different scales).
