Table 1.
Retrovirus | % cell death
|
|
---|---|---|
At 24 hr | At 48 hr | |
SRα | 12.7 ± 0.93 | 34.9 ± 1.34 |
SRα/Gfi-1 | 8.0 ± 0.08 | 25.6 ± 1.54 |
Live and dead cells were counted at 24 and 48 hr after IL-2 withdrawal. The percentage of dead cells was calculated from the ratios dead/(dead + live) cells. The numbers show the mean (±SEM) values of nine independent measurements for each time point (three subcultures of three independently infected cultures of 2780a cells). When a two-sided t test was used, the differences in the percentage of dead cells between the SRα- and SRα/Gfi-1-infected cultures were found to be statistically significant (at 24 hr P ≤ 0.0052 and at 48 hr P ≤ 0.00192).